Ramatercept (ActRIIB-Fc)
The Book of Peptides is not a clinic and not your doctor. We do not sell, prescribe, recommend, or personalize any compound, and no grade or ranking here is an endorsement. In the United States, most of these compounds are not FDA-approved and are sold for laboratory research only; a few are prescription drugs, and some are controlled substances or banned in sport. Possessing or administering an unapproved compound outside an authorized setting may be unlawful. Nothing here is a recommendation to buy, possess, or self-administer anything. Consult a licensed physician before any decision involving peptide use.
ACE-031 is a soluble ActRIIB-Fc decoy receptor that traps myostatin and related TGF-beta ligands, increasing lean mass; it is the most-searched myostatin-inhibitor research compound. Human development reached clinical trials in Duchenne muscular dystrophy but was halted over vascular side effects including nosebleeds and gum bleeding, so its safety profile is a genuine concern rather than a hypothetical. It is WADA-banned and has no approved use.
