Retatrutide + Cagrilintide
Layers cagrilintide's amylin-pathway satiety signal onto retatrutide's triple GLP-1/GIP/glucagon mechanism to hit four non-overlapping metabolic pathways at once — the aim is greater total fat loss, more complete appetite control, and the option to run each compound at a lower, better-tolerated dose.
Retatrutide alone hits three appetite-and-metabolism pathways at once; cagrilintide adds a <b>fourth, separate "fullness" pathway (amylin)</b> that acts in a different part of the brain.
